НЕАЛКОГОЛЬНАЯ ЖИРОВАЯ БОЛЕЗНЬ ПЕЧЕНИ: КОМОРБИДНОСТЬ, КЛИНИЧЕСКОЕ ЗНАЧЕНИЕ И МЕТОДЫ ДИАГНОСТИКИ ФИБРОЗА ПЕЧЕНИ
Ключевые слова:
неалкогольная жировая болезнь печени, фиброз печени, стеатогепатит, цирроз печени, транзиторная эластография, шкала NFS, шкала FIB-4, биопсия печени, метаболический синдром, инсулинорезистентностьАннотация
В статье проанализированы современные научные данные о патогенетических и клинико-эпидемиологических аспектах неалкогольной жировой болезни печени (НАЖБП), которая за последнее десятилетие вышла на первое место по распространенности среди заболеваний печени в России. Рассмотрены наиболее актуальные проблемы коморбидности при НАЖБП. Дана сравнительная характеристика различных методов диагностики фиброза печени с описанием их преимуществ и недостатков. Суммированы данные последних лет о прогностическом значении индексов, используемых для неинвазивной оценки фиброза печени при НАЖБП.
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